With 14 years of clinical research experience and growing market needs in dermatology product testing, Cliantha strategically acquired Hilltop Research in US & Canada to widen the horizon & service offerings.

With our DermRx division in North America and in India, we are able to conduct a wide variety of safety and efficacy trials for topical and transdermal drugs products. These trials can be conducted in a controlled in-house environment or on an outpatient basis. Cliantha has amassed a wide variety of specialty scientific instruments used in the conduct of our dermatology trials.


VASO Studies
HRIPT Studies
Adhesion Studies

Phase I Safety Trials

  • Acute Irritation or Primary Irritation (24-hour and 48-hour patch test)
  • Cumulative Irritation (14 day and 21day)
  • Contact Sensitization (Human Repeat Insult Patch Test [HRIPT])
  • Photo toxicity
  • Patch Testing
  • Photo-allergy
  • Pharmacokinetic Studies with capacity to house up to 48 subjects
  • Transdermal delivery systems (irritation, sensitization, adhesion)
  • Transdermal Patch Adhesion and Cold flow Studies

Efficacy Trials

  • Dermatology
    • Acne
    • Actinic Keratosis
    • Atopic dermatitis
    • Eczema
    • Head Lice, Scabies
    • Onychomycosis
    • Psoriasis
    • Rosacea
    • Seborrheic dermatitis
  • Hormone replacement therapy
  • Smoking cessation
  • Taste testing
  • Topical antibiotics
  • Vasoconstriction
  • Wound healing
  • Cold Sores, Herpes Labialis
    • Spontaneous
    • UV light induced
  • Diaper Rash
  • Transdermal Systems.
    • Lidocaine
    • Fentanyl
    • Rotigotine
    • Buprenorphine
  • Rivastigmine
  • Estradiol
  • Novel Compounds

Specialty Trials

Cliantha has extensive expertise with New Chemical Entities (NCE) and Bioequivalence with the following study types:

  • Contact Sensitization (Human Repeat Insult Patch Test [HRIPT])
  • Transdermal and Topical Bioequivalence
  • Skin Blanching - Vasoconstrictor Studies
  • Wear Studies
  • Cumulative Irritation (14 and 21 day studies)

Our Legacy Research

Cliantha has years of experience in conducting and analyzing Dermatology studies for pharmaceutical, biotechnology, generic and personal healthcare companies. We have expertise in conducting the following clinical research.

  • Patch testing (primary and cumulative irritation, sensitization)
  • Vasoconstriction (Skin Blanching)
  • Phototoxicity and photo allergy
  • Comedogenicity
  • Antiperspirant and deodorant*
  • Anti-aging
  • Hyperhidrosis Laser Treatment
  • Skin Biopsies
  • Skin lightening
  • Pediatric (diaper rash, disposable diapers/wipes, safety, infant eczema, product taste test)
  • Acne (cosmetic cleansing, anti-acne studies, OTC and Rx acne product studies and trials)
  • Sunscreen safety, durability and use trials in both adults and children
  • Mildness/moisturization (FCAT/LCAT studies, long- and short-term dry skin/moisturization)
  • Feminine hygiene (tampon and incontinence)
  • Cold sore, Herpes Labialis (naturally occurring and UVR-induced)
  • Head lice
  • Ocular safety (sting and instillation for topical products, home-use for cosmetics)
  • Wound care/wound healing (dermabrasion model, incisional wounds, tape-stripping, and SLS challenge)
  • Dry mouth
  • Cyberceuticals
  • Footwear, Athletic Clothing testing.
  • Fitness Wristbands and "wearables"
  • Chapped lips
  • Cleansing Efficacy (make-up removal)
  • Exfoliation
  • Cosmetic Use
  • Foot care, cracked heel